The stress models were conventionally made by giving a physical stress such as dipping the animals into the water, restraining them in the restrainers or giving an electrical shock. On the other hand this stress box is designed to make a stress model closer to the case of humans. The animals which do not receive any physical stress are emotionally affected by the animal which receives an electrical shock through the floor grid, finally inducing a gastric ulcer on the mucosa. It is considered a psychological stress. Therefore, the box can be used to assess the effect of the drugs like therapeutic agents for peptic ulcers, anti-anxiety or anti-depressant agents.
The system consists of a CBX-303 communication box, a CBX-CT cycle timer, a CSG-001 3-channel electrical shock generator and a MCS-01 Clip-Mount CS Presentation Unit. The communication box is available in two types —– CBX-303R for rats and CBX-303M for mice. Custom-made boxes are also available upon request.
The center and the 4 corner out of the 9 compartments are the psychological stress area and the remaining 4 compartments are the physical stress area where electrical shock is delivered. The color of the compartment dividers is clear so that the animal in the center compartment and the animals in the four corner compartments may receive psychological stress from the four directions and two directions, respectively. The color of the outside surface is not clear.
The ceiling (lid) is made of clear polyvinyl chloride with openings (1 ea/compartment) so that Light and Tone as well as air can be introduced.
CBX-303R COMMUNICATION BOX
|Chamber||Outside Surface : Polyvinyl Chloride(Dark)
Compartment Divider : Polyvinyl Chloride(Clear)
Lid : Polyvinyl Chloride(Clear)
|Division Dimension||W200 x D200 x H500 mm|
|Grid||Stainless : O.D.6 mm every 20 mm|
|Grid Block||Polyvinyl Chloride|
|Isolation Plate||Polyvinyl Chloride(Clear) x 4 ea|
|Chamber Stand||Zinc-plated steel Pipe with Plastic Coating|
|Dimensions||W690 x D690 x H1,023 mm(Stand included)|
CBX-CT CYCLE TIMER
|Setting||By digital SW, toggle SW|
|Digital SW|| TIMES - 1-1000 - Number of Cyclen
ITI - 1-199 - Waiting Period (sec)
CS1 - 0-190 - Warning Period (sec)
CS2 - 0-19 - Warning Period (sec)
UCS - 0.1-19 - Stimulation Period (sec)
|Toggle SW||TONE(CS1, CS2, UCS) ON/OFF of TONE output
LIGHT(CS1, CS2, UCS) ON/OFF of LIGHT output
|START SW||Starts the preset program|
|STOP SW||Stops the program (Double Click)|
|Display||LED ( RUN, TONE, LIGHT, SHOCK )|
|Output||Open Collector (30VDC 30mA)|
|Dimensions||W320 x D230 x H120 mm|
|Weight||Approx. 3 kg|
|Power||100V AC 50/60Hz 1A|
CSG-001 3-CH SHOCK GENERATOR
Current level adjustable by a rotary switch.
Current Intensity: 0.4, 0.6, 0.8, 1.0, 1.2 mA
Display : LED Comes on during current delivery
|Compliance Voltage||1400Vp-p AC 50/60 Hz|
|CS1||TONE (24VDC) Controlled by a variable resistor|
|CS2||LIGHT 100VAC(200W max.)|
|Dimensions||W320 x D230 x H80 mm|
|Power||100V AC 50/60Hz 3A|
CSG-001 is a 4-line shock generator scrambler used for the Communication Box CBX-303 which is divided into the 9 (3×3) compartments. One or two animals in a channel (one row) receives an electrical shock since the animals which receive an electrical shock or do not are arranged in turn. The shocker is equipped with the three independent power supplies so as to deliver as equal electrical shock as possible to the objects in a stable manner. Shock intensity can be set at five (5) levels by a rotary switch.
MCS-01 CLIP-MOUNT CS PRESENTATION UNIT
Related Product :MFS-01 Foot-Shock Stress System
Specifications are subject to change without notice.